APOB Antibody - Cat. #: CSB-PA318254

SKU: CSB-PA318254

Size :50ul

Clone Number:

Aliases:Apo B 100 antibody; Apo B antibody; Apo B-100 antibody; Apo B-48 antibody; Apo B100 antibody; Apo B48 antibody; ApoB 100 antibody; ApoB 48 antibody; APOB antibody; APOB_HUMAN antibody; Apolipoprotein B (including Ag(x) antigen) antibody; Apolipoprotein B 100 antibody; Apolipoprotein B 48 antibody; Apolipoprotein B antibody; Apolipoprotein B-48 antibody; Apolipoprotein B100 antibody; Apolipoprotein B48 antibody; FLDB antibody; LDLCQ4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P04114

Immunogen:Synthetic peptide of Human APOB

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:15-1:50

Background:This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:APOB

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction