Anti-ZMYND8 Antibody Picoband®

SKU: A06830-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ZMYND8

Specificity:

Background: Protein kinase C-binding protein 1 is an enzyme that in humans is encoded by the ZMYND8 gene. The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.

Immunogen: E.coli-derived human ZMYND8 recombinant protein (Position: M1-Q1087).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Fossey, S. C., Kuroda, S., Price, J. A., Pendleton, J. K., Freedman, B. I., Bowden, D. W. Identification and characterization of PRKCBP1, a candidate RACK-like protein. Mammalian Genome 11: 919-925, 2000. 2. Gross, M. B. Personal Communication. Baltimore, Md. 3/28/2014. 3. Shen, H., Xu, W., Guo, R., Rong, B., Gu, L., Wang, Z., He, C., Zheng, L., Hu, X., Hu, Z., Shao, Z.-M., Yang, P., Wu, F., Shi, Y. G., Shi, Y., Lan, F. Suppression of enhancer overactivation by a RACK7-histone demethylase complex. Cell 165: 331-342, 2016.

Uniprot ID: Q9ULU4

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 150 kDa

Calculated Molecular Weight: 104553 MW

Gene ID: 23613

Protein Name: MYND-type zinc finger-containing chromatin reader ZMYND8

Gene Full Name: zinc finger MYND-type containing 8

Synonyms: CTCL associated antigen se14 3; KIAA1125; PRKCBP1; PRO2893; RACK7; ZMYND8