Anti-Zebrafish CYP11C1 Antibody

SKU: AZA0A8M6YV96

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Zebrafish

Applications: IHC

Application Details: Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Zebrafish

Gene Name: CYP11C1

Specificity:

Background: Predicted to enable steroid 11-beta-monooxygenase activity. Acts upstream of or within cortisol metabolic process; male gonad development; and mating behavior. Predicted to be located in mitochondrial membrane and synapse. Predicted to be active in mitochondrial inner membrane. Is expressed in Leydig cell; brain; and pleuroperitoneal region. Used to study congenital adrenal hyperplasia. Human ortholog(s) of this gene implicated in several diseases, including congenital adrenal hyperplasia; corticosterone methyloxidase deficiency 1; diabetes mellitus (multiple); hypertension (multiple); and primary hyperaldosteronism (multiple). Orthologous to several human genes including CYP11B1 (cytochrome P450 family 11 subfamily B member 1).

Immunogen: E.coli-derived Zebrafish CYP11C1 recombinant protein (Position: D23-H701).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference:

Uniprot ID: A0A8M6YV96

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 791124

Protein Name: steroid 11beta-monooxygenase

Gene Full Name: cytochrome P450, family 11, subfamily C, polypeptide 1

Synonyms: cyp11c1; cyp11b2