Anti-ZC3H7A Antibody Picoband®

SKU: A15075-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ZC3H7A

Specificity:

Background: ZC3H7A (Zinc Finger CCCH-Type Containing 7A, also known as ZC3H7; HSPC055; ZC3HDC7), a member of CCCH gene family, is located on human chromosome 16p13.13. ZC3H7A is associated with some diseases, including Endometrial Stromal Tumor and Endometrial Stromal Sarcoma. An important paralog of this gene is ZC3H7B. The CCCH zinc finger motif has been found in proteins from organisms ranging from man to yeast. The CCCH proteins are a large family of zinc finger containing C3H-type motifs and much evidences proved that they may be RNA-binding proteins functioning in RNA processing. In mouse, tristetraprolin, a protein containing two CCCH zinc fingers, binds ly to AU-rich elements within the 3'-untranslated region of target transcripts to facilitate mRNA degradation. Zfp36l2, like its better-known relative TTP, is a mRNA-binding and destabilizing protein, functions in the physiological control of female fertility at the level of early embryonic development. The PIE-1 is an essential regulator of Caenorhabditis elegans germ cell fate that segregates with the germ lineage by inhibition of transcription or activation of protein expression from maternal RNAs.

Immunogen: E.coli-derived human ZC3H7A recombinant protein (Position: Q13-R717).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Wang, D. , Guo, Y. , Wu, C. , Yang, G. , Li, Y. , & Zheng, C. . (2008). Genome-wide analysis of ccch zinc finger family in arabidopsis and rice. Bmc Genomics, 9(1), 44. 2. Jian, L. , Song, W. , Gail, T. , Kolattukudy, P. E. , Fu, M. , & Mark, I. . (2008). Genome-wide survey and expression profiling of ccch-zinc finger family reveals a functional module in macrophage activation. PLoS ONE, 3(8), e2880.

Uniprot ID: Q8IWR0

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 111 kDa

Calculated Molecular Weight: 19908 MW

Gene ID: 29066

Protein Name: Zinc finger CCCH domain-containing protein 7A

Gene Full Name: zinc finger CCCH-type containing 7A

Synonyms: ZC3H7A; ZC3H7; ZC3HDC7; HSPC055; Zinc finger CCCH domain-containing protein 7A