Anti-Synip/STXBP4 Antibody Picoband®

SKU: A08343-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: STXBP4

Specificity:

Background: Enables syntaxin binding activity. Involved in several processes, including positive regulation of cell cycle G1/S phase transition; positive regulation of keratinocyte proliferation; and protein stabilization. Located in extracellular exosome.

Immunogen: E.coli-derived human Synip/STXBP4 recombinant protein (Position: D57-E481).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Min, J., Okada, S., Kanzaki, M., Elmendorf, J. S., Coker, K. J., Ceresa, B. P., Syu, L.-J., Noda, Y., Saltiel, A. R., Pessin, J. E. Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes. Molec. Cell 3: 751-760, 1999. Note: Erratum: Molec. Cell 4: following 142, 1999. 2. Saito, T., Okada, S., Yamada, E., Ohshima, K., Shimizu, H., Shimomura, K., Sato, M., Pessin, J. E., Mori, M. Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta-HC-9 cell. J. Biol. Chem. 278: 36718-36725, 2003. 3. Yamada, E., Okada, S., Saito, T., Ohshima, K., Sato, M., Tsuchiya, T., Uehara, Y., Shimizu, H., Mori, M. Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles. J. Cell Biol. 168: 921-928, 2005.

Uniprot ID: Q6ZWJ1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 68 kDa

Calculated Molecular Weight:

Gene ID: 252983

Protein Name: Syntaxin-binding protein 4

Gene Full Name: syntaxin binding protein 4

Synonyms: STXBP4; Syntaxin-binding protein 4; Syntaxin 4-interacting protein; STX4-interacting protein; Synip