Anti-SLUG/SNAI2 Antibody Picoband®

SKU: PB9439

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: IHC,WB

Application Details: Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Rat

Gene Name: SNAI2

Specificity: No cross reactivity with other proteins.

Background: SLUG is also known as SNAI2. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SLUG, identical to the related mouse and rat sequences.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: SNAI2 snail homolog 2 (Drosophila) 2. Cohen ME, Yin M, Paznekas WA, Schertzer M, Wood S, Jabs EW (Oct 1998). Human SLUG gene organization, expression, and chromosome map location on 8q. Genomics 51 (3): 468–71. 3. Rhim H, Savagner P, Thibaudeau G, Thiery JP, Pavan WJ (Jan 1998). Localization of a neural crest transcription factor, Slug, to mouse chromosome 16 and human chromosome 8. Mamm Genome 8 (11): 872–3.

Uniprot ID: O43623

Host: Rabbit

Concentration: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross reactivity with other proteins

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 30 kDa

Calculated Molecular Weight: 29986 MW

Gene ID: 6591

Protein Name: Zinc finger protein SNAI2

Gene Full Name: snail family transcriptional repressor 2

Synonyms: Protein snail homolog 2; SLUG; SLUGH; SLUGH1; SNAI2; WS2D; Zinc finger protein SNAI2