Anti-SHCD/SHC4 Antibody Picoband®

SKU: A10841-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SHC4

Specificity:

Background: Predicted to enable receptor tyrosine kinase binding activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within several processes, including apoptotic process; positive regulation of cell population proliferation; and stem cell differentiation. Predicted to be located in postsynaptic membrane. Predicted to be active in plasma membrane.

Immunogen: E.coli-derived human SHCD/SHC4 recombinant protein (Position: Q57-Q519).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Ahmed, S. B. M., Prigent, S. A. A nuclear export signal and oxidative stress regulate ShcD subcellular localisation: a potential role for ShcD in the nucleus. Cell. Signal. 26: 32-40, 2014. 2. Fagiani, E., Giardina, G., Luzi, L., Cesaroni, M., Quarto, M., Capra, M., Germano, G., Bono, M., Capillo, M., Pelicci, P., Lanfrancone, L. RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas. Cancer Res. 67: 3064-3073, 2007. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 02/27/2017.

Uniprot ID: Q6S5L8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 69 kDa

Calculated Molecular Weight: 29370 MW

Gene ID: 399694

Protein Name: SHC-transforming protein 4

Gene Full Name: SHC adaptor protein 4

Synonyms: hShcD; Rai like protein; RaLP; SH2 domain protein C4; SHC transforming protein 4; SHC transforming protein D; SHC4; SHCD