Anti-RING2 / RING1B / RNF2 Rabbit Monoclonal Antibody

SKU: M01209

Size: 100 μl

Storage: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Form: Liquid

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,Flow Cytometry

Application Details: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
FC 1:50

Gene Name: RNF2

Specificity:

Background:

Immunogen: A synthesized peptide derived from human RING2 / RING1B / RNF2 E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.

Clonality: Monoclonal

Contents: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Affinity-chromatography

Reconstitution:

Reference:

Uniprot ID: Q99496

Host: Rabbit

Concentration: 0.5mg/ml

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site:

Clone Number: Clone: AEDC-18

Observed Molecular Weight: 17 kDa

Calculated Molecular Weight: 123799 MW

Gene ID: 6045

Protein Name: E3 ubiquitin-protein ligase RING2

Gene Full Name: ring finger protein 2

Synonyms: BAP 1; BAP1; DING; HIP2 interacting protein 3; HIPI3; Protein DinG; RING finger protein 1B; ring finger protein 2; RING finger protein BAP 1; RING1B; RING2; RNF2