Anti-RAP80 Monoclonal Antibody

SKU: M06262

Size: 100 μl

Storage: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Form: Liquid

Reactivity: Human

Applications: WB,IHC,ICC,IF

Application Details: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200

Gene Name: UIMC1

Specificity:

Background:

Immunogen: A synthesized peptide derived from human RAP80 Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) .

Clonality: Monoclonal

Contents: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Affinity-chromatography

Reconstitution:

Reference:

Uniprot ID: Q96RL1

Host: Rabbit

Concentration: 0.5mg/ml

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site:

Clone Number: Clone: ADCH-21

Observed Molecular Weight: 70,90 kDa

Calculated Molecular Weight: 13911 MW

Gene ID: 51720

Protein Name: BRCA1-A complex subunit RAP80

Gene Full Name: ubiquitin interaction motif containing 1

Synonyms: BRCA1 A complex subunit RAP80; RAP80; Receptor associated protein 80; RXRIP110; UIMC1; X2HRIP110