Anti-Protein C inhibitor/SERPINA5 Antibody Picoband®

SKU: A01916-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: IHC,WB

Application Details: Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, Human
Western blot, 0.1-0.5μg/ml, Human, Rat

Gene Name: SERPINA5

Specificity: No cross reactivity with other proteins.

Background: Protein C inhibitor (PCI), also known as SERPINA5, is serine protease inhibitor of serpin type that is found in most tissues and fluids, including blood plasma, seminal plasma and urine of human. It is a 52kD glycoprotein and belongs to serine protease inhibitor (Serpin) super family of protein. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. This gene is mapped on the q arm of chromosome 14.

Immunogen: E.coli-derived human SERPINA5 recombinant protein (Position: S86-P406). Human SERPINA5 shares 66% amino acid (aa) sequence identity with mouse SERPINA5.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Laurell M, Christensson A, Abrahamsson PA, Stenflo J, Lilja H (April 1992). Protein C inhibitor in human body fluids. Seminal plasma is rich in inhibitor antigen deriving from cells throughout the male reproductive system. The Journal of Clinical Investigation. 89 (4): 1094–101. 2. Pratt CW, Church FC (May 1992). Heparin binding to protein C inhibitor (PDF). The Journal of Biological Chemistry. 267 (13): 8789–94. 3. Suzuki K, Nishioka J, Hashimoto S (1983). Protein C inhibitor. Purification from human plasma and characterization. The Journal of Biological Chemistry. 258 (1): 163–8.

Uniprot ID: P05154

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 46 kDa

Calculated Molecular Weight: 45675 MW

Gene ID: 5104

Protein Name: Plasma serine protease inhibitor

Gene Full Name: serpin family A member 5

Synonyms: PAI3; PCI; PLANH3; PROCI; Protein C inhibitor; SERPINA5