Anti-PARP3 Antibody Picoband®

SKU: A03762-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat,Monkey

Applications: WB,IHC,ICC,IF,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Monkey, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PARP3

Specificity:

Background: Poly [ADP-ribose] polymerase 3 is an enzyme that in humans is encoded by the PARP3 gene. The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen: E.coli-derived human PARP3 recombinant protein (Position: Q162-Q498). Human PARP3 shares 82.2% amino acid (aa) sequence identity with mouse and rat PARP3.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Augustin, A., Spenlehauer, C., Dumond, H., Menissier-de Murcia, J., Piel, M., Schmit, A.-C., Apiou, F., Vonesch, J.-L., Kock, M., Bornens, M., de Murcia, G. PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression. J. Cell Sci. 116: 1551-1562, 2003. 2. Johansson, M. A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues. Genomics 57: 442-445, 1999.

Uniprot ID: Q9Y6F1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 60 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 10039

Protein Name: Protein mono-ADP-ribosyltransferase PARP3

Gene Full Name: poly(ADP-ribose) polymerase family member 3

Synonyms: PARP3; ADPRT3; ADPRTL3; Protein mono-ADP-ribosyltransferase PARP3; ADP-ribosyltransferase diphtheria toxin-like 3; ARTD3; DNA ADP-ribosyltransferase PARP3; EC 2.4.2.-; IRT1; NAD(+)ADP-ribosyltransferase 3; ADPRT-3; Poly [ADP-ribose] polymerase 3; PARP-3; hPARP-3; Poly[ADP-ribose] synthase 3; pADPRT-3