Anti-PAP/ACP3 Antibody Picoband®

SKU: A02082-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ACP3

Specificity:

Background: Prostatic acid phosphatase (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway.

Immunogen: E.coli-derived human PAP/ACP3 recombinant protein (Position: E150-D386).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Fong, L., Brockstedt, D., Benike, C., Breen, J. K., Strang, G., Ruegg, C. L., Engleman, E. G. Dendritic cell-based xenoantigen vaccination for prostate cancer immunotherapy. J. Immun. 167: 7150-7156, 2001. 2. Li, S. S.-L., Sharief, F. S. The prostatic acid phosphatase (ACPP) gene is localized to human chromosome 3q21-q23. Genomics 17: 765-766, 1993. 3. Munch, J., Rucker, E., Standker, L., Adermann, K., Goffinet, C., Schindler, M., Wildum, S., Chinnadurai, R., Rajan, D., Specht, A., Gimenez-Gallego, G., Sanchez, P. C., and 9 others. Semen-derived amyloid fibrils drastically enhance HIV infection. Cell 131: 1059-1071, 2007.

Uniprot ID: P15309

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 45-50 kDa

Calculated Molecular Weight: 45 kDa

Gene ID: 55

Protein Name: Prostatic acid phosphatase

Gene Full Name: acid phosphatase 3

Synonyms: acid phosphatase, prostate; ACP 3; ACP3; ACPP; PAP; Prostatic acid phosphatase