Anti-OSBPL8 Antibody Picoband®

SKU: A08408-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: OSBPL8

Specificity:

Background: Oxysterol-binding protein-related protein 8 is a protein that in humans is encoded by the OSBPL8 gene. This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants.

Immunogen: E.coli-derived human OSBPL8 recombinant protein (Position: D33-K889).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Chung, J., Torta, F., Masai, K., Lucast, L., Czapla, H., Tanner, L. B., Narayanaswamy, P., Wenk, M. R., Nakatsu, F., De Camilli, P. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts. Science 349: 428-432, 2015. 2. Jaworski, C. J., Moreira, E., Li, A., Lee, R., Rodriguez, I. R. A family of 12 human genes containing oxysterol-binding domains. Genomics 78: 185-196, 2001. 3. Lehto, M., Laitinen, S., Chinetti, G., Johansson, M., Ehnholm, C., Staels, B., Ikonen, E., Olkkonen, V. M. The OSBP-related protein family in humans. J. Lipid Res. 42: 1203-1213, 2001.

Uniprot ID: Q9BZF1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 120 kDa

Calculated Molecular Weight: 82457 MW

Gene ID: 114882

Protein Name: Oxysterol-binding protein-related protein 8

Gene Full Name: oxysterol binding protein like 8

Synonyms: OSBPL8; KIAA1451; ORP8; OSBP10; Oxysterol-binding protein-related protein 8; ORP-8; OSBP-related protein 8