Anti-NTN4 Antibody Picoband®

SKU: A07052-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,Flow Cytometry

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Gene Name: NTN4

Specificity:

Background: This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants.

Immunogen: E.coli-derived human NTN4 recombinant protein (Position: C端). Human NTN4 shares 81% amino acid (aa) sequence identity with mouse NTN4.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Koch, M., Murrell, J. R., Hunter, D. D., Olson, P. F., Jin, W., Keene, D. R., Brunken, W. J., Burgeson, R. E. A novel member of the netrin family, beta-netrin, shares homology with the beta chain of laminin: identification, expression, and functional characterization. J. Cell Biol. 151: 221-234, 2000. 2. Larrieu-Lahargue, F., Welm, A. L., Thomas, K. R., Li, D. Y. Netrin-4 induces lymphangiogenesis in vivo. Blood 115: 5418-5426, 2010. 3. Zhang, C., Meng, F., Wang, C., Guo, H., Fan, M., Liu, S., Zhou, R., He, F. Identification of a novel alternative splicing form of human netrin-4 and analyzing the expression patterns in adult rat brain. Molec. Brain Res. 130: 68-80, 2004.

Uniprot ID: Q9HB63

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 70 kDa

Calculated Molecular Weight: 70 kDa

Gene ID: 59277

Protein Name: Netrin-4

Gene Full Name: netrin 4

Synonyms: NTN4; Netrin-4; Beta-netrin; Hepar-derived netrin-like protein