Anti-NDEL1 Antibody Picoband®

SKU: A02478-2

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: NDEL1

Specificity:

Background: Nuclear distribution protein nudE-like 1 is a protein that in humans is encoded by the NDEL1 gene. This gene encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome X.

Immunogen: E.coli-derived human NDEL1 recombinant protein (Position: K80-C320).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Burdick, K. E., Kamiya, A., Hodgkinson, C. A., Lencz, T., DeRosse, P., Ishizuka, K., Elashvili, S., Arai, H., Goldman, D., Sawa, A., Malhotra, A. K. Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding. Hum. Molec. Genet. 17: 2462-2473, 2008. 2. Hayashi, M. A. F., Portaro, F. C. V., Bastos, M. F., Guerreiro, J. R., Oliveira, V., Gorrao, S. S., Tambourgi, D. V., Sant'Anna, O. A., Whiting, P. J., Camargo, L. M., Konno, K., Brandon, N. J., Camargo, A. C. M. Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1. Proc. Nat. Acad. Sci. 102: 3828-3833, 2005. 3. Mori, D., Yamada, M., Mimori-Kiyosue, Y., Shirai, Y., Suzuki, A., Ohno, S., Saya, H., Wynshaw-Boris, A., Hirotsune, S. An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics. Nature Cell Biol. 11: 1057-1068, 2009.

Uniprot ID: Q9GZM8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 38 kDa

Calculated Molecular Weight: 22105 MW

Gene ID: 81565

Protein Name: Nuclear distribution protein nudE-like 1

Gene Full Name: nudE neurodevelopment protein 1 like 1

Synonyms: EOPA; MITAP1; Mitosin associated protein 1; NDEL1; NUDEL; Protein Nudel