Anti-MTBP Antibody Picoband®

SKU: A08842-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: MTBP

Specificity:

Background: This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation.

Immunogen: E.coli-derived human MTBP recombinant protein (Position: K106-K866). Human MTBP shares 76.6% amino acid (aa) sequence identity with mouse MTBP.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Boyd, M. T., Vlatkovic, N., Haines, D. S. A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2. J. Biol. Chem. 275: 31883-31890, 2000. 2. Boyd, M. T., Zimonjic, D. B., Popescu, N. C., Athwal, R., Haines, D. S. Assignment of the MDM2 binding protein gene (MTBP) to human chromosome band 8q24 by in situ hybridization. Cytogenet. Cell Genet. 90: 64-65, 2000.

Uniprot ID: Q96DY7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 100 kDa

Calculated Molecular Weight: 102 kDa

Gene ID: 27085

Protein Name: Mdm2-binding protein

Gene Full Name: MDM2 binding protein

Synonyms: hMTBP; Mdm2 binding protein; MDM2BP; MTBP