Anti-IFIT2 Antibody Picoband®

SKU: A04428-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC/IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: IFIT2

Specificity:

Background: Enables RNA binding activity. Involved in antiviral innate immune response and positive regulation of apoptotic process. Located in endoplasmic reticulum.

Immunogen: E.coli-derived human IFIT2 recombinant protein (Position: N23-E458). Human IFIT2 shares 62.2% amino acid (aa) sequence identity with mouse IFIT2.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Daffis, S., Szretter, K. J., Schriewer, J., Li, J., Youn, S., Errett, J., Lin, T.-Y., Schneller, S., Zust, R., Dong, H., Thiel, V., Sen, G. C., Fensterl, V., Klimstra, W. B., Pierson, T. C., Buller, R. M., Gale, M., Jr., Shi, P.-Y., Diamond, M. S. 2-prime-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature 468: 452-456, 2010. 2. Lafage, M., Clauss, I., Couez, D., Simonetti, J., Wathelet, M. G., Huez, G. The interferon- and virus-inducible IFI-56K and IFI-54K genes are located on human chromosome 10 at bands q23-q24. Genomics 13: 458-460, 1992. 3. Wathelet, M. G., Szpirer, J., Nols, C. B., Clauss, I. M., De Wit, L., Islam, M. Q., Levan, G., Horisberger, M. A., Content, J., Szpirer, C., Huez, G. A. Cloning and chromosomal location of human genes inducible by type I interferon. Somat. Cell Molec. Genet. 14: 415-426, 1988.

Uniprot ID: P09913

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 55 kDa

Calculated Molecular Weight: 55 kDa

Gene ID: 3433

Protein Name: Interferon-induced protein with tetratricopeptide repeats 2

Gene Full Name: interferon induced protein with tetratricopeptide repeats 2

Synonyms: IFI 54K; IFI 54; GARG 39; G10P2; CIG-42