Anti-HTR3E Antibody Picoband®

SKU: A09183-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: HTR3E

Specificity:

Background: This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Immunogen: E.coli-derived human HTR3E recombinant protein (Position: V26-R229).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Kapeller, J., Houghton, L. A., Monnikes, H., Walstab, J., Moller, D., Bonisch, H., Burwinkel, B., Autschbach, F., Funke, B., Lasitschka, F., Gassler, N., Fischer, C., and 10 others. First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome. Hum. Molec. Genet. 17: 2967-2977, 2008. 2. Karnovsky, A. M., Gotow, L. F., McKinley, D. D., Piechan, J. L., Ruble, C. L., Mills, C. J., Schellin, K. A. B., Slightom, J. L., Fitzgerald, L. R., Benjamin, C. W., Roberds, S. L. A cluster of novel serotonin receptor 3-like genes on human chromosome 3. Gene 319: 137-148, 2003. 3. Niesler, B., Frank, B., Kapeller, J., Rappold, G. A. Cloning, physical mapping and expression analysis of the human 5-HT(3) serotonin receptor-like genes HTR3C, HTR3D and HTR3E. Gene 310: 101-111, 2003.

Uniprot ID: A5X5Y0

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 51 kDa

Calculated Molecular Weight: 51 kDa

Gene ID: 285242

Protein Name: 5-hydroxytryptamine receptor 3E

Gene Full Name: 5-hydroxytryptamine receptor 3E

Synonyms: HTR3E; 5-hydroxytryptamine receptor 3E; 5-HT3-E; 5-HT3E; Serotonin receptor 3E