Anti-Glucagon Gcg Antibody (Monoclonal, K79bB10)

SKU: MA1047

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rabbit,Rat

Applications: IF,IHC

Application Details: Immunohistochemistry (Paraffin-embedded Section), 1-2μg/ml, Human, mouse, rat, rabbit
Immunofluorescence, 5 μg/ml, Human

Gene Name: GCG

Specificity: No cross reactivity with other proteins.

Background: Glucagon is a member of a multigene family that includes secretin. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. The human glucagon gene is approximately 9.4 kb long and contains 6 exons and 5 introns, and assigned to 2q36-2q37.

Immunogen: Polymerized porcine glucagon.

Clonality: Monoclonal

Contents: Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3. *This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Ascites

Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Reference: 1. Schroeder, W. T.; Lopez, L. C.; Harper, M. E.; Saunders, G. F. : Localization of the human glucagon gene (GCG) to chromosome segment 2q36-37. Cytogenet. Cell Genet. 38: 76-79, 1984. 2. White, J. W.; Saunders, G. F. : Structure of the human glucagon gene. Nucleic Acids Res. 14: 4719-4730, 1986.

Uniprot ID: P06883

Host: Mouse

Concentration: Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Mouse IgG1

Phospho_site:

Clone Number: Clone: K79bB10

Observed Molecular Weight: 50 kDa

Calculated Molecular Weight: 20846 MW

Gene ID: Human(2641), Mouse(14526), Rat(24952)

Protein Name: Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

Gene Full Name: Glucagon

Synonyms: GLP1; GLP2; glicentin-related polypeptide; glucagon-like peptide 1; glucagon-like peptide 2