Anti-FMO5 Antibody Picoband®

SKU: PA2108

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: WB

Application Details: Western blot, 0.1-0.5μg/ml, Human

Gene Name: FMO5

Specificity: No cross reactivity with other proteins.

Background: Dimethylaniline monooxygenase[N-oxide-forming] 5 also known as FMO 5 is an enzyme that in humans is encoded by the FMO5 gene. By fluorescence in situ hybridization, this gene was assigned to human chromosome 1q21.1. FMO5 is not an efficient drug-metabolizing enzyme and that it may have an alternative physiologic role. FMO5 transcripts play an important role in progesterone-regulated in breast cancer cells specifically under the control of the progesterone receptor B-isoform.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human FMO5, different from the related rat sequence by one amino acid, and different from the related mouse sequence by two amino acids.

Clonality: Polyclonal

Contents: Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Gelb, B. D., Zhang, J., Cotter, P. D., Gershin, I. F., Desnick, R. J. Physical mapping of the human connexin 40 (GJA5), flavin-containing monooxygenase 5, and natriuretic peptide receptor A genes on 1q21. Genomics 39: 409-411, 1997. 2. Miller, M. M., James, R. A., Richer, J. K., Gordon, D. F., Wood, W. M., Horwitz, K. B.Progesterone regulated expression of flavin-containing monooxygenase 5 by the B-isoform of progesterone receptors: implications for tamoxifen carcinogenicity. J. Clin. Endocr. Metab. 82: 2956-2961, 1997. 3. Overby, L. H., Buckpitt, A. R., Lawton, M. P., Atta-Asafo-Adjei, E., Schulze, J., Philpot, R. M. Characterization of flavin-containing monooxygenase 5(FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog. Arch. Biochem. Biophys. 317: 275-284, 1995.

Uniprot ID: P49326

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 60 kDa

Calculated Molecular Weight: 60221 MW

Gene ID: 2330

Protein Name: Flavin-containing monooxygenase 5

Gene Full Name: flavin containing dimethylaniline monoxygenase 5

Synonyms: Dimethylaniline oxidase 5; FMO 5; FMO5