Anti-Fascin 2/FSCN2 Antibody Picoband®

SKU: A07840-2

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,WB

Application Details: Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5μg/ml, -

Gene Name: FSCN2

Specificity: No cross reactivity with other proteins.

Background: Fascin-2 is a protein that in humans is encoded by the FSCN2 gene. It is mapped to 17q25.3. This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human Fascin 2/FSCN2 recombinant protein (Position: M1-K167).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Hillier LD, Lennon G, Becker M, et al. (1997). Generation and analysis of 280,000 human expressed sequence tags. Genome Res. 6 (9): 807–28. 2. Tubb BE, Bardien-Kruger S, Kashork CD, et al. (2000). Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes. Genomics. 65 (2): 146–56. 3. Saishin Y, Ishikawa R, Ugawa S, et al. (2000). Retinal fascin: functional nature, subcellular distribution, and chromosomal localization. Invest. Ophthalmol. Vis. Sci. 41 (8): 2087–95.

Uniprot ID: O14926

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 60 kDa

Calculated Molecular Weight: 49229 MW

Gene ID: 25794

Protein Name: Fascin-2

Gene Full Name: fascin actin-bundling protein 2, retinal

Synonyms: Fascin-2; Retinal fascin; FSCN2