Anti-CXXC5 Antibody Picoband®

SKU: A06865-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,Flow Cytometry

Application Details: Western blot, 0.25-0.5 μg/ml, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Gene Name: CXXC5

Specificity:

Background: The protein encoded by this gene is a retinoid-inducible nuclear protein containing a CXXC-type zinc finger motif. The encoded protein is involved in myelopoiesis, is required for DNA damage-induced p53 activation, regulates the differentiation of C2C12 myoblasts into myocytes, and negatively regulates cutaneous wound healing. Several transcript variants encoding the same protein have been found for this gene.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CXXC5. Human CXXC5 shares 100% amino acid (aa) sequence identity with both mouse and rat CXXC5.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Andersson, T., Sodersten, E., Duckworth, J. K., Cascante, A., Fritz, N., Sacchetti, P., Cervenka, I., Bryja, V., Hermanson, O. CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. J. Biol. Chem. 284: 3672-3681, 2009. 2. Aras, S., Pak, O., Sommer, N., Finley Jr., R., Huttemann, M., Weissmann, N., Grossman, L. I. Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5, and CHCHD2. Nucleic Acids Res. 41: 2255-2266, 2013. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 4/22/2009.

Uniprot ID: Q7LFL8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 38 kDa

Calculated Molecular Weight: 33 kDa

Gene ID: 51523

Protein Name: CXXC-type zinc finger protein 5

Gene Full Name: CXXC finger protein 5

Synonyms: CXXC finger 5; CXXC5; CXXC-type zinc finger protein 5; HSPC195; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; Retinoid-inducible nuclear factor; RINF; TCCCIA00297