Anti-CPEB4 Antibody Picoband®

SKU: A06139-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: CPEB4

Specificity:

Background: Cytoplasmic polyadenylation element binding protein 4 (CPEB4) is a sequence-specific RNA-binding protein that participates in translational control. CPEB4 is a member of the CPEB family, which includes CPEB1, CPEB2, CPEB3, and CPEB4, all of which share structure and sequence identity in the C-terminal RNA-binding domain (RBD). CPEB4 has two domains: one that is structured for RNA binding and one that is unstructured and low complexity that has no known function.

Immunogen: E.coli-derived human CPEB4 recombinant protein (Position: D3-N462).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Nagase, T., Kikuno, R., Hattori, A., Kondo, Y., Okumura, K., Ohara, O. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 7: 347-355, 2000. 2. Ortiz-Zapater, E., Pineda, D., Martinez-Bosch, N., Fernandez-Miranda, G., Iglesias, M., Alameda, F., Moreno, M., Eliscovich, C., Eyras, E., Real, F. X., Mendez, R., Navarro, P. Key contribution of CPEB4-mediated translational control to cancer progression. Nature Med. 18: 83-90, 2011. 3. Parras, A., Anta, H., Santos-Galindo, M., Swarup, V., Elorza, A., Nieto-Gonzalez, J. L., Pico, S., Hernandez, I. H., Diaz-Hernandez, J. I., Belloc, E., Rodolosse, A., Parikshak, N. N., Penagarikano, O., Fernandez-Chacon, R., Irimia, M., Navarro, P., Geschwind, D. H., Mendez, R., Lucas, J. J. Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature 560: 441-446, 2018.

Uniprot ID: Q17RY0

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 90 kDa

Calculated Molecular Weight: 17828 MW

Gene ID: 80315

Protein Name: Cytoplasmic polyadenylation element-binding protein 4

Gene Full Name: cytoplasmic polyadenylation element binding protein 4

Synonyms: CPE binding protein 4; CPE BP4; CPEB4; hCPEB 4; KIAA1673