Anti-Carboxypeptidase A/CPA1 Antibody Picoband®

SKU: A05985-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: WB

Application Details: Western blot, 0.1-0.5μg/ml

Gene Name: CPA1

Specificity: No cross reactivity with other proteins.

Background: Carboxypeptidase A1 is an enzyme that in humans is encoded by the CPA1 gene. This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Carboxypeptidase A, which shares 84.8% and 87% amino acid (aa) sequence identity with mouse and rat Carboxypeptidase A, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: CPA1 carboxypeptidase A1 (pancreatic). 2. Witt, H., Beer, S., Rosendahl, J., Chen, J.-M., Candak, G. R., Masamune, A., Bence, M., Szmola, R., Oracz, G., Macek, M., Jr., Bhatia, E., Steigenberger, S., and 54 others. Variants in CPA1 are strongly associated with early onset chronic pancreatitis. Nature Genet. 45: 1216-1220, 2013.

Uniprot ID: P15085

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 47 kDa

Calculated Molecular Weight: 80420 MW

Gene ID: 1357

Protein Name: Carboxypeptidase A1

Gene Full Name: carboxypeptidase A1

Synonyms: Carboxypeptidase A1; CPA; CPA1