Anti-Calmodulin/CALM 1/2/3 Antibody Picoband®

SKU: A06609-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: WB

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat

Gene Name: CALM1/2/3

Specificity:

Background: This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Calmodulin/CALM 1/2/3.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Abzhanov, A., Kuo, W. P., Hartmann, C., Grant, B. R., Grant, P. R., Tabin, C. J. The calmodulin pathway and evolution of elongated beak morphology in Darwin's finches. Nature 442: 563-567, 2006. 2. Abzhanov, A., Protas, M., Grant, R. B., Grant, P. R., Tabin, C. J. Bmp4 and morphological variation of beaks in Darwin's finches. Science 305: 1462-1465, 2004. 3. Berchtold, M. W., Egli, R., Rhyner, J. A., Hameister, H., Strehler, E. E. Localization of the human bona fide calmodulin genes CALM1, CALM2, and CALM3 to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3. Genomics 16: 461-465, 1993.

Uniprot ID: P0DP23/P0DP24/P0DP25

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 17 kDa

Calculated Molecular Weight: 17 kDa

Gene ID: 801805808

Protein Name:

Gene Full Name: Calmodulin

Synonyms: CALM; CALM1; CALM2; CALM3; CALML2; Calmodulin; CaM; CAM1; CAM2; CAM3; CAMB; CAMC; CAMIII; PHKD; PHKD3