Anti-C7orf30/MALSU1 Antibody Picoband®

SKU: A12786

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: ELISA,Flow Cytometry,IF,IHC,WB

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: MALSU1

Specificity:

Background: MALSU1 is a gene on chromosome 7 in humans that encodes the protein MALSU1. This protein localizes to mitochondria and is probably involved in mitochondrial translation or the biogenesis of the large subunit of the mitochondrial ribosome. C7orf30, also known asMALSU1, is a member ofthe iojap protein family. Itwas predicted to enable ribosomal large subunit binding activity. ItwasInvolved in negative regulation of mitochondrial translation and ribosomal large subunit biogenesis.

Immunogen: E.coli-derived human MALSU1 recombinant protein (Position: A30-E234). Human C7orf30/MALSU1 shares 74.4% amino acid (aa) sequence identity with mouse MALSU1.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Hartz, P. A. Personal Communication. Baltimore, Md. 5/7/2012. 2. Rorbach, J., Gammage, P. A., Minczuk, M. C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome. Nucleic Acids Res. 40: 4097-4109, 2012. Note: Erratum: Nucleic Acids Res. 44: 992 only, 2016. 3. Wanschers, B. F. J., Szklarczyk, R., Pajak, A., van den Brand, M. A. M., Gloerich, J., Rodenburg, R. J. T., Lightowlers, R. N., Nijtmans, L. G., Huynen, M. A. C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation. Nucleic Acids Res. 40: 4040-4051, 2012.

Uniprot ID: Q96EH3

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 24 kDa

Calculated Molecular Weight:

Gene ID: 115416

Protein Name: Mitochondrial assembly of ribosomal large subunit protein 1

Gene Full Name: mitochondrial assembly of ribosomal large subunit 1

Synonyms: C7orf30; MALSU1