Anti-BAT3/BAG6 Antibody Picoband®

SKU: A00967-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,IF,IHC,ICC,WB,Flow Cytometry

Application Details: Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml
Immunocytochemistry/Immunofluorescence, 5μg/ml
Flow Cytometry(Fixed), 1-3μg/1x10⁶ cells
ELISA, 0.1-0.5 μg/ml

Gene Name: BAG6

Specificity: No cross reactivity with other proteins.

Background: Large proline-rich protein BAT3 is a protein that in humans is encoded by the BAT3 gene. It is mapped to 6p21.33. This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: E. coli-derived human BAT3/BAG6 recombinant protein (D15-A88).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Banerji, J., Sands, J., Strominger, J. L., Spies, T. A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain. Proc. Nat. Acad. Sci. 87: 2374-2378, 1990. 2. Hessa, T., Sharma, A., Mariappan, M., Eshleman, H. D., Gutierrez, E., Hegde, R. S. Protein targeting and degradation are coupled for elimination of mislocalized proteins. Nature 475: 394-397, 2011. 3. Mariappan, M., Li, X., Stefanovic, S., Sharma, A., Mateja, A., Keenan, R. J., Hegde, R. S. A ribosome-associating factor chaperones tail-anchored membrane proteins. Nature 466: 1120-1124, 2010.

Uniprot ID: P46379

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 150 kDa

Calculated Molecular Weight:

Gene ID: 7917

Protein Name: Large proline-rich protein BAG6

Gene Full Name: BAG cochaperone 6

Synonyms: BAG 6; BAG6; BAT3; D6S52E; G3; HLA B associated transcript 3; Protein G3