Anti-AMOTL2 Antibody Picoband®

SKU: A06852

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,IF,ICC,WB

Application Details: Western blot, 0.1-0.5μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: AMOTL2

Specificity: No cross reactivity with other proteins.

Background: Angiomotin-like protein 2 is a protein that in humans is encoded by the AMOTL2 gene. Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). It mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene.

Immunogen: E. coli-derived human AMOTL2 recombinant protein (Position: A401-Q480).

Clonality: Polyclonal

Contents: Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Li, Z., Wang, Y., Zhang, M., Xu, P., Huang, H., Wu, D., Meng, A. The Amotl2 gene inhibits Wnt/B-catenin signaling and regulates embryonic development in zebrafish. J. Biol. Chem. 287: 13005-13015, 2012. 2. Wang, Y., Li, Z., Xu, P., Huang, L., Tong, J., Huang, H., Meng, A. Angiomotin-like2 gene (amotl2) is required for migration and proliferation of endothelial cells during angiogenesis. J. Biol. Chem. 286: 41095-41104, 2011.

Uniprot ID: Q9Y2J4

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 130-150 kDa

Calculated Molecular Weight: 86 kDa

Gene ID: 51421

Protein Name: Angiomotin-like protein 2

Gene Full Name: angiomotin like 2

Synonyms: AMOTL2; angiomotin like 2; Angiomotin like protein 2; KIAA0989; LCCP; Leman coiled coil protein