Anti-AMCase/CHIA Antibody Picoband®

SKU: A00437-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: WB,IHC,ELISA

Application Details: Western blot, 0.5-1 μg/ml, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: CHIA

Specificity:

Background: The protein encoded by this gene degrades chitin, which is found in the cell wall of most fungi as well as in arthropods and some nematodes. The encoded protein can also stimulate interleukin 13 expression, and variations in this gene can lead to asthma susceptibility. Several transcript variants encoding a few different isoforms have been found for this gene.

Immunogen: E.coli-derived human AMCase/CHIA recombinant protein (Position: L228-A476).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Boot, R. G., Blommaart, E. F. C., Swart, E., Ghauharali-van der Vlugt, K., Bijl, N., Moe, C., Place, A., Aerts, J. M. F. G. Identification of a novel acidic mammalian chitinase distinct from chitotriosidase. J. Biol. Chem. 276: 6770-6778, 2001. 2. Reese, T. A., Liang, H.-E., Tager, A. M., Luster, A. D., Van Rooijen, N., Voehringer, D., Locksley, R. M. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 447: 92-96, 2007. 3. Saito, A., Ozaki, K., Fujiwara, T., Nakamura, Y., Tanigami, A. Isolation and mapping of a human lung-specific gene, TSA1902, encoding a novel chitinase family member. Gene 239: 325-331, 1999.

Uniprot ID: Q9BZP6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 52 kDa

Calculated Molecular Weight: 52 kDa

Gene ID: 27159

Protein Name: Acidic mammalian chitinase

Gene Full Name: chitinase acidic

Synonyms: 2200003E03Rik; Acidic mammalian chitinase; AMCase; CHIA; CHIT2; chitinase; acidic; Lung specific protein TSA1902; RP5 1125M8.1; TSA1902