Anti-alpha 1 Sodium Potassium ATPase/ATP1A1 Antibody Picoband®

SKU: PB9482

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: IF,IHC,WB

Application Details: Western blot, 0.1-0.5μg/ml, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat
Immunofluorescence, 5 μg/ml, Human, Rat

Gene Name: ATP1A1

Specificity: No cross reactivity with other proteins.

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ATP1A1, different from the related mouse sequence by three amino acids, and from the related rat sequence by four amino acids.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: ATP1A1 ATPase, Na+/K+transporting, alpha 1 polypeptide. 2. Dunbar LA, Caplan MJ (2001). Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases.. J. Biol. Chem. 276 (32): 29617–20. 3. Xie Z, Cai T (2004). Na+-K+--ATPase-mediated signal transduction: from protein interaction to cellular function.. Mol. Interv. 3(3): 157–68.

Uniprot ID: P05023

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 100-113 kDa

Calculated Molecular Weight: 112896 MW

Gene ID: 476

Protein Name: Sodium/potassium-transporting ATPase subunit alpha-1

Gene Full Name: ATPase Na+/K+ transporting subunit alpha 1

Synonyms: ATP1A1; Na(+)/K(+) ATPase 1; Na(+)/K(+) ATPase alpha 1 subunit; Na+/K+ ATPase 1; Sodium potassium ATPase alpha 1 polypeptide; Sodium pump subunit alpha 1