Anti-ADAMTS13 Antibody Picoband®

SKU: A00586-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ADAMTS13

Specificity:

Background: ADAMTS13 (a disintegrin and metalloproteinase with athrombospondin type 1 motif, member 13), also known as VWFCP, is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood and degrades large vWf multimers, decreasing their activity. This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. This gene is mapped to 9q34.

Immunogen: E.coli-derived human ADAMTS13 recombinant protein (Position: D298-T1427).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Fujimura Y, Matsumoto M, Yagi H, et al. (2002). Von Willebrand factor-cleaving protease and Upshaw-Schulman syndrome.. Int. J. Hematol. 75 (1): 25–34. 2. Furlan M, Lämmle B (2001). Aetiology and pathogenesis of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome: the role of von Willebrand factor-cleaving protease. Best Pract Res Clin Haematol 14 (2): 437–54.

Uniprot ID: Q76LX8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 154 kDa

Calculated Molecular Weight:

Gene ID: 11093

Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 13

Gene Full Name: ADAM metallopeptidase with thrombospondin type 1 motif 13

Synonyms: ADAM TS 13; ADAM TS13; ADAMTS 13; ADAMTS13; C9orf8; DKFZp434C2322; FLJ42993; TTP; vWF cleaving protease; vWF CP; VWFCP