AMD Polyclonal Antibody

SKU: BT-AP14196

Size:100μL

Background:This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Research_area:Neuroscience; Signal transduction

Target_protein:PAM

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Peptidyl-glycine alpha-amidating monooxygenase

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P19021; Mouse: P97467; Rat: P14925

Synonyms:Peptidyl-glycine alpha-amidating monooxygenase ;PAM [Includes: Peptidylglycine alpha-hydroxylating monooxygenase ;PHM;EC 1.14.17.3; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase ;EC 4.3.2.5

GeneID:Human: 5066