AMACR Monoclonal Antibody

SKU: BT-MCA0152

Size:100μL

Background:This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Research_area:Signal transduction; Tags & cell markers; Metabolism; Cancer; Epigenetics and nuclear signaling

Target_protein:AMACR

applications:WB, IHC-p, IF, ICC, ELISA

Reactivity:Human,Mouse

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:Alpha-methylacyl-CoA racemase

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):N/A

UniProt accession:Human: Q9UHK6; Mouse: O09174

Synonyms:AMACR; Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase

GeneID:Human: 23600; Mouse: 17117