AKAP10 Antibody - Cat. #: CSB-PA001519ESR2HU

SKU: CSB-PA001519ESR2HU

Size :50ul

Clone Number:

Aliases:AKAP10A-kinase anchor protein 10 antibody; mitochondrial antibody; AKAP-10 antibody; Dual specificity A kinase-anchoring protein 2 antibody; D-AKAP-2 antibody; Protein kinase A-anchoring protein 10 antibody; PRKA10 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43572

Immunogen:Recombinant Human A-kinase anchor protein 10, mitochondrial protein (413-662AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:AKAP10

Research Areas:Signal transduction