AHR rabbit pAb

SKU: ES18432

Size: 100μL

Source:Rabbit

Applications:WB; IF

Reactivity:Human; Mouse;Rat;Fish

Dilution:WB 1:500-2000; IF/ICC 1:100-500

Immunogen:Synthesized peptide derived from human AHR AA range: 408-458

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:196

Human_swiss_prot_no:P35869

Subcellular_location:Cytoplasm . Nucleus . Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. .

Other_name:

Background:The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],