AGXT Antibody - Cat. #: CSB-PA256331

SKU: CSB-PA256331

Size :50ul

Clone Number:

Aliases:AGT antibody; AGT1 antibody; Agxt antibody; AGXT1 antibody; Alanine glyoxylate aminotransferase antibody; Alanine glyoxylate aminotransferase3 antibody; Alanine--glyoxylate aminotransferase antibody; EC 2.6.1.44 antibody; EC 2.6.1.51 antibody; Hepatic peroxisomal alanine glyoxylate aminotransferase antibody; Hepatic peroxisomal alanine:glyoxylate aminotransferase antibody; L alanine glyoxylate aminotransferase 1 antibody; MS773 antibody; PH1 antibody; Serine pyruvate aminotransferase antibody; Serine--pyruvate aminotransferase antibody; Serine--pyruvate aminotransferase, mitochondrial antibody; Serine:pyruvate aminotransferase antibody; SPAT antibody; SPT antibody; SPYA_HUMAN antibody; TLH6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P21549

Immunogen:Synthetic peptide of Human AGXT

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000

Background:Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:AGXT

Research Areas:Metabolism;Signal transduction