AF/LE Purified Anti-Human/Mouse KLRG-1 Antibody[2F1]

SKU: GBS-F12730

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:KLRG-1

Target Synonym:Klrg;CLEC15A;MAFA;MAFAL;KLRG1;HNK-1; Leu-7;Klrg;Mafa;Klrg1

Research Areas:Immunology

Conjugation:None (AF/LE)

Host:Syrian Hamster

Species reactivity:Human,Mouse

Application:FCM

Usage:

Isotype:Syrian Hamster IgG

Clonality:Monoclonal

Clone NO.:2F1

UNIProt ID:Q96E93;O88713;

Background:Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8⁺and CD4⁺cells, including CD4⁺and CD8⁺effector/memory cells, potent regulatory CD4⁺T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG2 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Mouse KLRG-1 protein

Buffer:Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:10219