AF/LE Purified Anti-Human CD14 Antibody[M5E2]

SKU: GBS-F12090

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD14

Target Synonym:monocyte differentiation antigen CD;CD14;soluble;CD14 antigen;CD14 molecule;monocyte differentiation antigen CD14;Myeloid cell-specific leucine-rich glycoprotein;LPS R;CD 14;CD_antigen=CD14;LPS-R;membrane-bound form;Mo2;Monocyte differentiation antigen CD14 urinary form;Myeloid cell specific leucine rich glycoprotein

Research Areas:Immunology;Stem Cells;Kits;Lysates;Other

Conjugation:None (AF/LE)

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG2a, κ

Clonality:Monoclonal

Clone NO.:M5E2

UNIProt ID:P08571

Background:The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD14 protein

Buffer:Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:929