ADA19 Polyclonal Antibody

SKU: BT-AP14127

Size:100μL

Background:This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions| including fertilization| muscle development| and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase| which may be involved in normal physiological processes such as cell migration| cell adhesion| cell-cell and cell-matrix interactions| and signal transduction. It is proposed to play a role in pathological processes| such as cancer| inflammatory diseases| renal diseases| and Alzheimer's disease.

Research_area:Signal transduction; Cancer; Cell biology

Target_protein:ADAM19

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Disintegrin and metalloproteinase domain-containing protein 19

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9H013; Mouse: O35674

Synonyms:Disintegrin and metalloproteinase domain-containing protein 19 ;ADAM 19;EC 3.4.24.-;Meltrin-beta;Metalloprotease and disintegrin dendritic antigen marker;MADDAM

GeneID:Human: 8728