ACVRL1 antibody , Cat. # FNab00131

SKU: FNab00131

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.

Immunogen:activin A receptor type II-like 1

Synonyms:Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I

Observed MW:56 kDa

Uniprot ID:P37023

Reactivity:Human

Tested Application:ELISA, WB, IHC, FC, IP

Recommended dilution:WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000

Gene ID:94

Research Area:Cardiovascular, Metabolism, Signal Transduction