ACMSD Antibody, FITC conjugated - Cat. #: CSB-PA851554LC01HU

SKU: CSB-PA851554LC01HU

Size :50ug

Clone Number:

Aliases:2 amino 3 carboxymuconate 6 semialdehyde decarboxylase antibody; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase antibody; acmsd antibody; ACMSD_HUMAN antibody; Aminocarboxymuconate semialdehyde decarboxylase antibody; Picolinate carboxylase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8TDX5

Immunogen:Recombinant Human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase protein (33-129AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ACMSD

Research Areas:Others