Acetyl Histone H1 (K25) Polyclonal Antibody

SKU: BT-AP00155

Size:100μL

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The H1 histone family member O, oocyte specific encoded is a replication-independent histone that is a member of the histone H1 family. H1FOO contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:H1FOO

applications:WB, IHC-p, ELISA

Reactivity:Human, Monkey

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Acetyl Histone H1 (K25) Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):21010

UniProt accession:Human: Q8IZA3; Mouse: Q8VIK3

Synonyms:H1FOO; H1OO; OSH1; Histone H1oo; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1

GeneID:Human: 132243