Size:100ug
Purification:Protein A+G purification
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:6C4
Isotype:IgG2b
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Immunogen:eukaryotic translation initiation factor 4E binding protein 1
Synonyms:4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I
Observed MW:12 kDa
Uniprot ID:Q13541
Reactivity:Human
Tested Application:ELISA, WB, IF
Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200
Gene ID:1978
Research Area:Cancer, Metabolism