See below for Detailed Description
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Size: 200ug. Other sizes are also available. Please Inquire.
In Stock: No
Lead time: 10-20 working days
Research Topic: Cell Biology
Uniprot ID: P09382
Gene Names: LGALS1
Organism: Homo sapiens (Human)
AA Sequence: ACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
Expression Region: 2-135aa
Sequence Info: Full Length
Tag Info: N-terminal 6xHis-SUMO-tagged
MW: 30.6 kDa
Alternative Name(s): 14KDA laminin-binding protein ;HLBP1414KDA lectin;Beta-galactoside-binding lectin L-14-IGalaptinHBLHPLLactose-binding lectin 1Lectin galactoside-binding soluble 1;Putative MAPK-activating protein PM12S-Lac lectin 1
Relevance: May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Reference: Cloning and nucleotide sequence of a full-length cDNA for human 14KDA beta-galactoside-binding lectin.Hirabayashi J., Ayaki K., Soma G., Kasai K.Biochim. Biophys. Acta 1008:85-91(1989)
Purity: Greater than 90% as determined by SDS-PAGE.
Storage Buffer: Tris-based buffer，50% glycerol
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.