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Recombinant Human General transcription factor IIF subunit 2(GTF2F2)

CSB-EP010005HU

Recombinant Human General transcription factor IIF subunit 2(GTF2F2)

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CAD$709.00

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Size: 200ug. Other sizes are also available. Please Inquire.

In Stock: No

Lead time: 10-20 working days

Research Topic: Transcription

Uniprot ID: P13984

Gene Names: GTF2F2

Organism: Homo sapiens (Human)

AA Sequence: AERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNEDLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAASENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYRHYQGEEKSD

Expression Region: 2-249aa

Sequence Info: Full Length

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

MW: 44.2 kDa

Alternative Name(s): ATP-dependent helicase GTF2F2General transcription factor IIF 30KDA subunitTranscription initiation factor IIF subunit beta ;TFIIF-betaTranscription initiation factor RAP30

Relevance: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.

Reference: Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II.Sopta M., Burton Z.F., Greenblatt J.Nature 341:410-414(1989)

Purity: Greater than 90% as determined by SDS-PAGE.

Storage Buffer: Tris-based buffer,50% glycerol

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

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