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Updated Date: Stock Protein updated on 20171018
Research areas: Tags & Cell Markers
Target / Protein: PNMA2
Biologically active: Not Tested
Expression system: E.coli
Species of origin: Homo sapiens (Human)
Delivery time: 3-7 business days
Uniprot ID: Q9UL42
AA Sequence: ALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMAGATLNQMLWCRLRELKDQGPPPSFLELMKVIREEEEEEASFENESIEEPEERDGYGRWNHE
Tag info: N-terminal 6xHis-SUMO-tagged
Expression Region: 2-361aa
Protein length: Partial
MW: 57.1 kDa
Alternative Name(s): 40KDA neuronal protein Onconeuronal antigen Ma2 Paraneoplastic neuronal antigen MM2
Relevance: Antibodies against PNMA2 are present in sera from patients suffering of paraneoplastic neurological disorders.
Reference: "A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer." Voltz R., Gultekin S.H., Rosenfeld M.R., Gerstner E., Eichen J., Posner J.B., Dalmau J. N. Engl. J. Med. 340:1788-1795(1999)
Purity: Greater than 85% as determined by SDS-PAGE.
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.