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Recombinant Larimichthys crocea Hepcidin(hamp)

CSB-EP010124LLH

Recombinant Larimichthys crocea Hepcidin(hamp)

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CAD$913.00

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>Several Other Sizes Are Also Available. Please Inquire. Default Size: 200ug

Updated Date: Stock Protein updated on 20171018

Research areas: Immunology

Target / Protein: hamp

Biologically active: Not Tested

Expression system: E.coli

Species of origin: Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea)

Delivery time: 3-7 business days

Uniprot ID: A1Z0M0

AA Sequence: RCRFCCRCCPRMRGCGICCRF

Tag info: NO-tagged

Expression Region: 65-85aa

Protein length: Full Length of Mature Protein

MW: 2.5 kDa

Alternative Name(s):

Relevance: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages Has very strong antibacterial activity against the marine Gram-negative bacteria V.alginolyticus (MIC=24 µM), V.fluvialis, V.harveyis (MIC=12 µM) and V.parahaemolyticus (MIC=6 µM). Has antibacterial activity against the Gram-negative bacteria A.hydrophila (MIC=6 µM), E.coli (MIC=24 µM), and E.coli BL21(DE3)plysS (MIC=6 µM), and the Gram-positive bacteria B.cereus (MIC=24 µM), B.subtilis (MIC=6 µM), C.glutamicum (MIC=3 µM), M.luteus (MIC=3 µM), M.lysodeikticus, S.aureus (MIC=6 µM) and S.epidermis (MIC=12 µM). Possesses antifungal activity against A.niger (MIC=24 µM), F.graminearum (MIC24 µM) and F.solani (MIC=24 µM), but lacks antifungal activity against the yeasts P.pastoris GS115 and C.albicans.

Reference: "Isolation and characterization of a hepcidin peptide from the head kidney of large yellow croaker, Pseudosciaena crocea." Zhang J., Yan Q., Ji R., Zou W., Guo G. Fish Shellfish Immunol. 26:864-870(2009)

Purity: Greater than 90% as determined by SDS-PAGE.

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

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