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Recombinant Helicobacter pylori Vacuolating cytotoxin autotransporter(vacA),partial

CSB-EP669657HUS

Recombinant Helicobacter pylori Vacuolating cytotoxin autotransporter(vacA),partial

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CAD$1,066.00

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>Several Other Sizes Are Also Available. Please Inquire. Default Size: 200ug

Updated Date: Stock Protein updated on 20170405

Research areas: Microbiology

Target / Protein: vacA

Biologically active: Not Tested

Expression system: E.coli

Species of origin: Helicobacter pylori (Campylobacter pylori)

Delivery time: 3-7 business days

Uniprot ID: Q48253

AA Sequence: KYEKPTNVWANAIGGTSLNNGSNASLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSNQANSLNSGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLQDLNQSYHYLAYSATTRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKSNSNQVALSNGSSSQHLFNANANVEARYYYGDTSYFYMNAGVLQEFARFGSNNAVSLNTFKVNATRNPLNTHARVMMGGELQLAKEVFLNLGVVYLHNLISNASHFASNLGMRYSF

Tag info: N-terminal 6xHis-SUMO-tagged

Expression Region: 1038-1310aa

Protein length: Partial

MW: 45.7 kDa

Alternative Name(s): Cleaved into the following 2 chains: Vacuolating cytotoxin Vacuolating cytotoxin translocator

Relevance: Induces vacuolation of eukaryotic cells. Causes ulceration and gastric lesions.

Reference: "Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration."Atherton J.C., Cao P., Peek R.M. Jr., Tummuru M.K., Blaser M.J., Cover T.L.J. Biol. Chem. 270:17771-17777(1995)

Purity: Greater than 90% as determined by SDS-PAGE.

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

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