{"product_id":"wtap-antibody-hrp-conjugated-cat-csb-pa618970lb01hu","title":"WTAP Antibody, HRP conjugated - Cat. #: CSB-PA618970LB01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:DKFZp686F20131 antibody; Female-lethal(2)D homolog antibody; FL2D_HUMAN antibody; hFL(2)D antibody; KIAA0105 antibody; MGC3925 antibody; Mum2 antibody; OTTHUMP00000017522 antibody; OTTHUMP00000017523 antibody; PNAS 132 antibody; PNAS-132 antibody; PNAS132 antibody; Pre mRNA splicing regulator WTAP antibody; Pre-mRNA-splicing regulator WTAP antibody; Putative pre mRNA splicing regulator female lethal 2D homolog antibody; Putative pre mRNA splicing regulator female lethal(2D) antibody; Putative pre-mRNA splicing regulator female lethal(2D) homolog antibody; putative pre-mRNA splicing regulator female-lethal(2D) antibody; Wilms tumor 1 associated protein antibody; Wilms tumor 1 associating protein antibody; Wilms tumor 1-associating protein antibody; Wilms' tumor 1 associating protein antibody; Wilms' tumour 1-associating protein antibody; WT1 associated protein antibody; WT1-associated protein antibody; WT1-associating protein antibody; wtap antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q15007\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Pre-mRNA-splicing regulator WTAP protein (1-151AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2\/M cell-cycle transition by binding to the 3\\' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:HRP\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:WTAP\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486699597924,"sku":"CSB-PA618970LB01HU","price":484.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_b36096a4-a550-4b27-89bd-c61db9524122.jpg?v=1660151675","url":"https:\/\/www.genebiosystems.com\/products\/wtap-antibody-hrp-conjugated-cat-csb-pa618970lb01hu","provider":"GeneBio ","version":"1.0","type":"link"}