{"product_id":"tpm1-antibody-cat-csb-pa171540","title":"TPM1 Antibody - Cat. #: CSB-PA171540","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:AA986836 antibody; AI854628 antibody; Alpha tropomyosin antibody; alpha-TM antibody; Alpha-tropomyosin antibody; C15orf13 antibody; cardiomyopathy; hypertrophic 3 antibody; CMD1Y antibody; CMH3 antibody; HTM alpha antibody; HTM-alpha antibody; OTTHUMP00000163688 antibody; sarcomeric tropomyosin kappa antibody; TM2 antibody; Tmpa antibody; TMSA antibody; Tpm-1 antibody; TPM1 antibody; TPM1_HUMAN antibody; tropomyosin 1 (alpha) antibody; tropomyosin 1 (alpha) isoform 1 antibody; tropomyosin 1 (alpha) isoform 2 antibody; tropomyosin 1 (alpha) isoform 3 antibody; tropomyosin 1 (alpha) isoform 4 antibody; tropomyosin 1 (alpha) isoform 5 antibody; tropomyosin 1 (alpha) isoform 6 antibody; tropomyosin 1 (alpha) isoform 7 antibody; Tropomyosin 1 antibody; Tropomyosin alpha 1 chain antibody; Tropomyosin alpha-1 chain antibody; Tropomyosin; skeletal muscle alpha antibody; Tropomyosin-1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P09493\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Fusion protein of Human TPM1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:TPM1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cardiovascular;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40482828255332,"sku":"CSB-PA171540","price":484.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_30500b88-0a8a-4124-af4e-7dd40148c1a5.jpg?v=1660057574","url":"https:\/\/www.genebiosystems.com\/products\/tpm1-antibody-cat-csb-pa171540","provider":"GeneBio ","version":"1.0","type":"link"}